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Yorkshire Terrier Legg-Calve-Perthes Disease

Overview

Of the various bone and joint-related conditions that can affect dogs, Legg-Calve-Perthes Disease (LCPD) is one that Yorkshire Terrier owners should be aware of. It is particularly relevant to those with puppies. Though it is not overly common, this often-crippling disease is seen with Yorkshire Terriers more than any other breed. It involves one of the two hind legs, often worsens quickly, can be very painful and debilitating, and requires prompt treatment. 

What is Legg-Calve-Perthes Disease? 

Legg-Calve-Perthes Disease, just like hip dysplasia, involves the head of the femur bone (the ball that fits into the socket in the pelvis, which makes up the hip joint). However, unlike dysplasia in which there is an abnormal fit or a loosening or slipping, with Legg-Calve-Perthes Disease there is necrosis; the bone starts to deteriorate and die. Without treatment, the structure of the hip eventually collapses. 

This is a degenerative disease, meaning that the condition increasingly worsens, and the affected area deteriorates over time.

This causes pain and mobility issues and can be crippling. In addition, Yorkshire Terriers affected by Legg-Calve-Perthes Disease develop osteoarthritis soon afterward, which is thought to be linked to small fractures and scar tissue that occurs with LCPD. Steps should be taken to help delay the onset of osteoarthritis and, once it develops, properly treat it, since arthritis itself can be painful and affect mobility. 

In most cases, Legg-Calve-Perthes Disease occurs in just one hip. 

Occurrence Rate with Yorkshire Terriers

LCPD affects small dogs under 20 lbs. (9 kg) much more often than larger breeds and commonly affects terriers. The Yorkshire Terrier is a breed that is extremely prone to Legg-Calve-Perthes Disease. In fact, the Orthopedic Foundation for Animals (OFA) has the Yorkshire Terrier ranked as the #1 breed that suffers from Legg-Calve-Perthes (as of 2018, found in 2.2% of 182 Yorkies given evaluations). 

Age of Onset

With Yorkshire Terriers, this most often manifests at a young age, between 4 and 12 months old. Though, in some cases, it may not be diagnosed until a little later, up to the 18-month mark. 

Causes

While the exact cause of Legg-Calve-Perthes Disease is still unknown, it does run in certain breeds and is thought to be connected to a lack of proper blood flow to the area that may be linked to clots within the blood vessels.

Symptoms

• Limping. This is usually the first sign and is often the only sign until the disease has advanced for several weeks. In most cases, a Yorkie will have a slight limp involving one of the hind legs, and it will progressively worsen over the course of 3 to 4 weeks. As it advances, it will turn quite severe with no weight at all being able to be placed onto the affected limb.  

Note that in rare cases, the condition can come on extremely quickly and worsen very suddenly and/or may involve both hind legs. 

Other signs include:

• Pain (a Yorkie may hold the leg in an odd manner, whine, want to retreat, or show other signs of discomfort). Pain levels usually increase if the leg is touched or manipulated. 
• Lameness (unable to move or control the leg)
• The affected leg may appear shorter
• Muscle atrophy/loss of muscle tone

How This is Diagnosed 

Diagnosis is usually made through physical examination and x-rays. 

Typically, several x-rays are taken over the course of days or weeks to look for changes/progression, which is indicative of Legg-Calve-Perthes Disease. 

It's common for the first round of x-rays to only show a slight flattening of the head of the femur. Additional x-rays will show a deterioration of the femur, which confirms the diagnosis. If x-rays are taken in later stages, it will show severe deformation and signs of arthritis. 

It is important to take a Yorkie to the veterinarian if Legg-Calve-Perthes Disease is suspected since non-surgical treatment can be effective if there is an early diagnosis. 

Treatment, Non-Surgical 

Though Legg-Calve-Perthes Disease with Yorkshire Terriers is a very serious condition, there are several non-surgical treatment options. These are most effective if the condition has been diagnosed early. 

This includes: 
 
• Very strict bed-rest. This involves preventing a dog from putting any weight onto the leg. A small crate is used to prevent any standing or walking. For bathroom needs only, a dog can be carried out of the crate and gently placed onto the grass; however, this is done on a very short leash so that they are not able to walk at all. This sort of strict bed rest may last 4 to 6 months. During this time, x-rays will be taken periodically to determine if the area is responding and healing. 

NSAIDs (non-steroidal anti-inflammatory drugs). One of the most common is Rimadyl, and this can help with both pain and inflammation. Because long-term usage can cause possible organ damage, the veterinarian will need to oversee dosing and a Yorkie will need to be carefully monitored. 

Corticosteroids. One of the most common is prednisone. Because there can be severe side effects, this is usually only given short-term. Even so, there may be changes in thirst or appetite and risk of susceptibility to infections. A Yorkie will need to be carefully monitored. 

Supplements. Certain supplements can help treat osteoarthritis, which is always linked to Legg-Calve-Perthes Disease and will be seen in the affected hip. Supplements that are given include Omega fatty acids (those with EPA and DHA, derived from wild fish are often best) and a combination of glucosamine and chondroitin with MSM and Coenzyme Q10 (CoQ10).

Additional treatment may involve laser therapy, acupuncture, massage, and/or non-weight bearing water therapy. 

Treatment, Surgical

If non-surgical treatment options do not resolve pain and mobility issues, in very severe cases, or when the diagnosis comes in late, surgery may be recommended. 

For larger dogs, total hip replacement is an option; however, toy breeds like the Yorkshire Terrier are not good candidates for this. Instead, surgery is performed to remove the head of the femur bone. Afterward, the body gradually repairs itself as tissue and muscle form in the area. In most cases, a dog no longer suffers from pain. Over the course of a year or so, mobility is restored to varying degrees. 

After surgery, there is a need for physical therapy and medication (including the aforementioned supplements) to aid in a dog's recovery.   
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